Public Meeting of the Chartered Science Advisory Board and the Science Advisory Board Chemical Assessment Advisory Committee

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Agenda

To conduct quality reviews of two draft SAB reports and consultations with EPA on: (1) activities to re-examine and consolidate EPA’s Human Toxicity Assessment Guidelines, and (2) new approach methods and reducing the use of laboratory animals for chronic and carcinogenicity testing.

Agenda. (PDF, 3 pp., 165,783 bytes)

Advisory Activity (or Activities) Discussed

Technical review of EPA’s new computable general equilibrium (CGE) model, SAGE

All-Ages Lead Model: Evaluation of the Theoretical Framework and Model

New Approach Methods and Reducing the Use of Laboratory Animals for Chronic and Carcinogenicity Testing

Consolidated Human Toxicity Assessment Guideline Design and Development


Agency Charge

Charge for Technical review of EPA’s new computable general equilibrium (CGE) model, SAGE (PDF, 5 pp., 267,621 bytes)

Charge for All-Ages Lead Model: Evaluation of the Theoretical Framework and Model (PDF, 1 pp., 72,522 bytes)

Charge for New Approach Methods and Reducing the Use of Laboratory Animals for Chronic and Carcinogenicity Testing (PDF, 2 pp., 137,167 bytes)

Charge for Consolidated Human Toxicity Assessment Guideline Design and Development (PDF, 6 pp., 352,333 bytes)

Agency Review Documents

Technical review of EPA’s new computable general equilibrium (CGE) model, SAGE
   PDF for Public Zip Files for SAGE CGE Model (PDF, pp., bytes)

All-Ages Lead Model: Evaluation of the Theoretical Framework and Model
   PDF for Technical Support Document for the All Ages Lead Model (AALM) – Parameters, Equations, and Evaluations (PDF, 333 pp., 3,972,330 bytes)

All-Ages Lead Model: Evaluation of the Theoretical Framework and Model
   PDF for Availability of the AALM (PDF, 1 pp., 69,632 bytes)

All-Ages Lead Model: Evaluation of the Theoretical Framework and Model
   PDF for Users Guide for the FORTRAN Version of the All Ages Lead Model (PDF, 20 pp., 785,368 bytes)

New Approach Methods and Reducing the Use of Laboratory Animals for Chronic and Carcinogenicity Testing
   PDF for New Approach Methods and Reducing the Use of Laboratory Animals for Chronic and Carcinogenicity Testing (PDF, 24 pp., 519,642 bytes)

Report(s) to Review:

Disclaimer Although not required to do so, EPA generally posts public comments submitted to the SAB, CASAC or Council and their subcommittees on the internet to make them easily available to the public. Posting of public comments is not an Agency endorsement of, or agreement with, any information or viewpoints presented in the public comment, nor is it an Agency endorsement of the quality or correctness of such information and viewpoints. In addition, mention of any trade names or commercial products in posted meeting material does not constitute a recommendation by EPA or the SAB for use.