EPA Science Advisory Board (SAB)

IRIS Assessment for Trimethylbenzenes

EPA Designated Federal Officer (DFO):Thomas Carpenter
Responsible Committee/Panel:Chemical Assessment Advisory Committee Augmented for the Review of the Draft IRIS Trimethylbenzene Assessment
A list of members can be found in the final report included in the Advisory Activity linked to this panel or committee.

See EPA’s PDF page to learn more about PDF files.

The EPA's Office of Research and Development (ORD) has developed a draft “IRIS Toxicological Review of Trimethylbenzenes “(August 2013), the first IRIS assessment developed for trimethylbenzenes, including 1,2,3-TMB; 1,2,4-TMB; 1,3,5-TMB. For this assessment, ORD evaluated experimental animal data and other relevant noncancer data The assessment includes an inhalation reference concentration, oral reference dose, and qualitative cancer descriptor for each isomer. The assessment does not include a quantitative cancer assessment

ORD has requested SAB peer review of its August 2013 toxicological review of trimethylbenzenes.

Agency Charge . (PDF, 7 pp., 204,518 bytes)

Agency Review Document(s):

PDF for Toxicological Review of Trimethylbenzenes In Support of Summary Information the Integrated Risk Information System (IRIS): Supplemental Information . (PDF, 284 pp., 10,060,050 bytes)

PDF for Toxicological Review for Trimethylbenzenes In Support of Summary and Information on the Integrated Risk Information System . (PDF, 161 pp., 2,063,688 bytes)