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The EPA's Office of Research and Development (ORD) has developed a draft “Toxicological Review of Ammonia” (August 2013), which reassesses the toxicity of ammonia posted to the IRIS database. For the 2013 draft assessment, ORD evaluated epidemiological data, experimental animal data, and other relevant data from studies of the noncancer and cancer effects of ammonia. This reassessment includes an inhalation RfC and a qualitative cancer descriptor. The assessment does not include an oral reference dose (RfD) or a quantitative cancer assessment.
ORD has requested SAB peer review of its August 2013 toxicological review of ammonia.