EPA Science Advisory Board (SAB)

Perfluorooctanoic Acid Human Health Risk Assessment

EPA Designated Federal Officer (DFO):Suhair Shallal
Responsible Committee/Panel:Perfluorooctanoic Acid Review PanelA list of members can be found in the final report included in the Advisory Activity linked to this panel or committee.

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EPA's Office of Pollution Prevention and Toxics requested the Science Advisory Board review the preliminary risk assessment of Perfluorooctanoic Acid (PFOA) with special emphasis on: a) the use of serum data as a measure of internal dose; b) the use of serum levels from parental animals as a surrogate for levels in offspring; c) the use of pharmacokinetic information to estimate the internal dose in the pups; d) the use of the data to provide a range of possible MOEs;and e) other assumptions made by the Agency.