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IRIS Assessment for Benzo[a]pyrene

EPA Designated Federal Officer (DFO):Diana Wong

Responsible Committee/Panel:Ad Hoc Augmented Standing Committee Being Formed

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EPA’s Office of Research and Development has developed a draft Toxicological Review of Benzo[a]pyrene (August 2013), which updates a 1987 assessment of the toxicity of benzo[a]pyrene posted to the IRIS database. The 2013 draft assessment contains a qualitative characterization of the hazards for benzo[a]pyrene, including a cancer descriptor of the chemical’s human carcinogenic potential, cancer risk estimates for oral, inhalation and dermal exposure, and noncancer toxicity values for chronic oral (reference dose) and inhalation (reference concentration) exposure. The draft assessment also includes the IRIS Program’s first dermal slope factor.
ORD has requested SAB peer review of its August 2013 draft toxicological review for benzo[a]pyrene.

EPA background information related to the review document:

IRIS Toxicological Review of Benzo[a]pyrene (Public Comment Draft) (Aug 2013)

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