EPA Science Advisory Board (SAB)

IRIS Assessment for Ammonia

EPA Designated Federal Officer (DFO):Suhair Shallal
Responsible Committee/Panel:Chemical Assessment Advisory Committee Augmented for the Review of the Draft IRIS Ammonia Assessment

See EPA’s PDF page to learn more about PDF files.


The EPA's Office of Research and Development (ORD) has developed a draft “Toxicological Review of Ammonia” (August 2013), which reassesses the toxicity of ammonia posted to the IRIS database. For the 2013 draft assessment, ORD evaluated epidemiological data, experimental animal data, and other relevant data from studies of the noncancer and cancer effects of ammonia. This reassessment includes an inhalation RfC and a qualitative cancer descriptor. The assessment does not include an oral reference dose (RfD) or a quantitative cancer assessment.

ORD has requested SAB peer review of its August 2013 toxicological review of ammonia.

Agency Charge . (PDF, 5 pp., 153,233 bytes)

Agency Review Document(s):

PDF for EPA's Toxicological Review of Ammonia. (PDF, 103 pp., 1,283,924 bytes)

PDF for Supplemental for Toxicological Review of Ammonia. (PDF, 110 pp., 1,490,917 bytes)